Abstract

This article provides a comprehensive overview of N,N-Diethyl-m-Toluamide (CAS No. 134-62-3) Analytical Grade Standard. It delves into the chemical properties, uses, analytical methods, safety considerations, and regulatory aspects of this compound. The article aims to serve as a reference for scientists, researchers, and regulatory bodies involved in the handling and analysis of N,N-Diethyl-m-Toluamide.

Introduction to N,N-Diethyl-m-Toluamide (CAS No. 134-62-3) Analytical Grade Standard

N,N-Diethyl-m-Toluamide, also known as DEET, is a widely used chemical compound with the CAS No. 134-62-3. It is an organic compound belonging to the class of toluamide derivatives. DEET is primarily known for its insect repellent properties and is used in various formulations to protect against mosquito-borne diseases such as malaria, dengue fever, and Zika virus. This article aims to provide a detailed analysis of the analytical grade standard of DEET, covering its chemical properties, uses, analytical methods, safety considerations, and regulatory aspects.

Chemical Properties of N,N-Diethyl-m-Toluamide

N,N-Diethyl-m-Toluamide is a colorless to pale yellow liquid with a characteristic odor. It has a molecular formula of C₈H₁₁NO and a molecular weight of 151.19 g/mol. DEET is highly volatile and has a boiling point of approximately 212°C. It is soluble in organic solvents such as alcohol, acetone, and ether but is only slightly soluble in water. These chemical properties make DEET suitable for various applications, including its use as an insect repellent.

Uses of N,N-Diethyl-m-Toluamide

The primary use of N,N-Diethyl-m-Toluamide is as an insect repellent. It is widely used in various formulations, including sprays, lotions, and sticks, to protect humans and animals from mosquito bites. DEET is effective against a wide range of insects, including mosquitoes, ticks, and flies. Additionally, DEET is used in agricultural applications to protect crops from insect pests and in veterinary medicine to prevent tick-borne diseases in animals.

Analytical Methods for N,N-Diethyl-m-Toluamide

The analytical grade standard of N,N-Diethyl-m-Toluamide requires precise and reliable analytical methods for its quantification. Common analytical techniques used for the determination of DEET include gas chromatography (GC), high-performance liquid chromatography (HPLC), and spectrophotometry. These methods allow for the accurate measurement of DEET concentration in various matrices, ensuring compliance with regulatory standards.

Safety Considerations for N,N-Diethyl-m-Toluamide

While N,N-Diethyl-m-Toluamide is effective as an insect repellent, it is important to consider its safety profile. DEET is generally considered safe when used as directed, but high concentrations or prolonged exposure can cause adverse effects. Symptoms of DEET toxicity include headache, dizziness, nausea, and skin irritation. It is crucial to follow the recommended guidelines for the use of DEET, including avoiding contact with eyes and applying it sparingly.

Regulatory Aspects of N,N-Diethyl-m-Toluamide

The regulatory framework for N,N-Diethyl-m-Toluamide varies by country and region. In the United States, the Environmental Protection Agency (EPA) regulates the use of DEET in insect repellent products. The EPA sets guidelines for the concentration of DEET in products and ensures that they are safe for public use. Similarly, other regulatory bodies around the world have their own regulations and guidelines for the use and sale of DEET-containing products.

Conclusion

In conclusion, N,N-Diethyl-m-Toluamide (CAS No. 134-62-3) Analytical Grade Standard is a crucial compound with various applications, particularly as an insect repellent. This article has provided a detailed analysis of its chemical properties, uses, analytical methods, safety considerations, and regulatory aspects. Understanding these factors is essential for scientists, researchers, and regulatory bodies involved in the handling and analysis of DEET. As the demand for effective insect repellents continues to grow, the importance of maintaining high standards in the production and use of N,N-Diethyl-m-Toluamide cannot be overstated.

Keywords

N,N-Diethyl-m-Toluamide, DEET, CAS No. 134-62-3, analytical grade standard, insect repellent, chemical properties, uses, analytical methods, safety considerations, regulatory aspects.