Abstract

This article provides a comprehensive identification of 2-Phenoxyethanol (CAS No. 122-99-6), a widely used organic compound. It covers the chemical structure, physical properties, identification methods, safety considerations, applications, and regulatory aspects of this compound. The aim is to offer a detailed understanding of 2-Phenoxyethanol, its uses, and the importance of accurate identification in various industries.

Introduction to 2-Phenoxyethanol (CAS No. 122-99-6)

2-Phenoxyethanol, also known as ethyl phenyl ether, is a colorless, flammable liquid with a mild, characteristic odor. It is widely used in various industries, including pharmaceuticals, cosmetics, and agriculture, as a preservative and solvent. The CAS number 122-99-6 is a unique identifier for this compound, which is crucial for its accurate identification and regulation.

Chemical Structure

The chemical structure of 2-Phenoxyethanol consists of an ethyl group attached to a phenyl group, which is a benzene ring with a hydroxyl group attached to one of its carbon atoms. This structure gives the compound its unique properties, such as its solubility in water and its ability to act as a preservative.

Physical Properties

2-Phenoxyethanol has several physical properties that are important for its identification and use. It has a boiling point of approximately 174°C and a melting point of around -25°C. It is slightly soluble in water, with a solubility of about 1.5 g per 100 mL at 20°C. These properties make it suitable for use in formulations that require a balance between solubility and stability.

Identification Methods

Accurate identification of 2-Phenoxyethanol is essential for quality control and regulatory compliance. Several methods can be used to identify this compound:

1. **Nuclear Magnetic Resonance (NMR) Spectroscopy**: NMR spectroscopy is a powerful tool for determining the structure of organic compounds. It can provide detailed information about the molecular structure, including the connectivity of atoms and the environment of each atom.

2. **Infrared (IR) Spectroscopy**: IR spectroscopy is used to identify functional groups within a molecule. The characteristic peaks in the IR spectrum of 2-Phenoxyethanol can be used to confirm its presence.

3. **Gas Chromatography-Mass Spectrometry (GC-MS)**: GC-MS is a combination of gas chromatography and mass spectrometry, which allows for the separation and identification of volatile compounds. This method is particularly useful for identifying 2-Phenoxyethanol in complex mixtures.

Safety Considerations

While 2-Phenoxyethanol is widely used, it is important to consider its safety profile. The compound is toxic if ingested or inhaled, and it can cause irritation to the skin and eyes. Proper handling and storage procedures are necessary to minimize the risk of exposure.

Applications

2-Phenoxyethanol has a wide range of applications due to its preservative and solvent properties. It is commonly used in:

1. **Pharmaceuticals**: As a preservative in eye drops, vaccines, and other injectable medications.
2. **Cosmetics**: To prevent microbial contamination in lotions, shampoos, and other personal care products.
3. **Agriculture**: As a fungicide and insecticide in agricultural applications.

Regulatory Aspects

The use of 2-Phenoxyethanol is regulated by various agencies around the world. In the United States, the Food and Drug Administration (FDA) regulates its use in pharmaceuticals and cosmetics. The European Union has established maximum allowable concentrations for its use in food and cosmetics. Accurate identification of 2-Phenoxyethanol is crucial for compliance with these regulations.

Conclusion

2-Phenoxyethanol (CAS No. 122-99-6) is a versatile organic compound with a range of applications. Its accurate identification is essential for quality control, safety, and regulatory compliance. Through the use of various analytical techniques, such as NMR, IR, and GC-MS, the chemical structure and properties of 2-Phenoxyethanol can be determined. Understanding its safety profile and regulatory status is also critical for its proper use in various industries.

Keywords

2-Phenoxyethanol, CAS No. 122-99-6, chemical structure, identification methods, safety considerations, applications, regulatory aspects, NMR, IR, GC-MS