This article provides a comprehensive identification of Isopropyl Myristate (CAS 110-27-0), a versatile organic compound widely used in various industries. The article delves into the chemical properties, physical characteristics, synthesis methods, applications, safety considerations, and regulatory aspects of Isopropyl Myristate, offering a detailed understanding of this compound's identity and significance in different sectors.
Isopropyl Myristate, with the chemical formula C18H36O2, is an ester derived from isopropyl alcohol and myristic acid. It is commonly known for its pleasant odor and is used as a solvent, emulsifier, and fragrance ingredient in numerous products. This article aims to provide a thorough identification of Isopropyl Myristate, covering its chemical, physical, and practical aspects.
Isopropyl Myristate is a colorless to pale yellow liquid at room temperature. It has a melting point of approximately 27-29°C and a boiling point of around 285-287°C. The compound is insoluble in water but soluble in organic solvents such as ethanol, ether, and chloroform. Its molecular weight is 284.48 g/mol, and it has a molecular formula of C18H36O2. The chemical structure of Isopropyl Myristate consists of an isopropyl group attached to a myristic acid chain, making it a long-chain fatty acid ester.
Isopropyl Myristate has a characteristic odor reminiscent of almonds and is often used in perfumery. It is a non-volatile liquid, which makes it suitable for use in products that require a stable and long-lasting fragrance. The compound is also known for its excellent solvating properties, which allow it to dissolve a wide range of organic compounds, making it a valuable ingredient in the formulation of various products.
The synthesis of Isopropyl Myristate typically involves the esterification reaction between isopropyl alcohol and myristic acid. This reaction can be carried out using an acid catalyst, such as sulfuric acid or hydrochloric acid, to facilitate the formation of the ester bond. The process is usually conducted under reflux conditions to ensure complete reaction and to recover the unreacted starting materials. The resulting product is then purified through distillation to obtain the desired purity of Isopropyl Myristate.
Isopropyl Myristate finds extensive use in the cosmetic and pharmaceutical industries. It is commonly used as a solvent in the formulation of skin care products, such as lotions and creams, due to its ability to dissolve other active ingredients and enhance their absorption into the skin. In the pharmaceutical sector, it serves as a lubricant and solvent in tablet coatings and as an excipient in parenteral preparations. Additionally, Isopropyl Myristate is employed in the production of fragrances, plastics, and as a plasticizer in certain applications.
Isopropyl Myristate is considered safe for use in cosmetics and pharmaceuticals, although it is important to follow the recommended concentration guidelines. The compound has been evaluated by various regulatory agencies, including the U.S. Food and Drug Administration (FDA) and the European Union's Cosmetics Directive. It is classified as a non-irritant and is generally recognized as safe (GRAS) for use in food, pharmaceuticals, and cosmetics. However, as with any chemical, proper handling and storage are essential to prevent any potential risks.
In conclusion, Isopropyl Myristate (CAS 110-27-0) is a versatile organic compound with a wide range of applications in various industries. Its chemical properties, physical characteristics, synthesis methods, and safety considerations have been thoroughly discussed in this article. Understanding the identity and significance of Isopropyl Myristate is crucial for its proper use and regulation in the cosmetic, pharmaceutical, and other sectors.
Keywords: Isopropyl Myristate, CAS 110-27-0, chemical properties, physical characteristics, synthesis, applications, safety, regulatory aspects.
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