Abstract

This article provides a comprehensive overview of Octocrylene, a chemical compound with the formula C24H27NO2 and CID 22571. Octocrylene is widely used in the cosmetic industry as a UV filter to protect skin from harmful ultraviolet radiation. The article delves into the chemical properties, synthesis methods, applications, safety concerns, regulatory status, and environmental impact of Octocrylene, offering a detailed understanding of its role in personal care products.

Introduction to Octocrylene

Octocrylene, chemically known as 2-(2-hydroxy-5-methylphenyl)-5-(2-hydroxyethoxyphenyl)-4-methylbenzophenone, is a synthetic organic compound. It is primarily used as a UV filter in sunscreens and skincare products due to its effectiveness in absorbing UVB and UVA rays. Octocrylene is known for its high UV protection factor (SPF) and is considered safe for use on the skin when applied in appropriate concentrations.

Chemical Properties of Octocrylene

Octocrylene has a molecular weight of 371.44 g/mol and is a white to off-white crystalline solid. It is insoluble in water but soluble in organic solvents such as acetone, ethanol, and ethyl acetate. The compound has a melting point of approximately 76-78°C and a boiling point of around 410°C. Its chemical structure consists of a benzophenone core with two phenyl groups substituted at the 2- and 5-positions, and a hydroxyethyl group at the 5-position.

Synthesis of Octocrylene

The synthesis of Octocrylene involves a multi-step process that typically starts with the preparation of the 2-hydroxy-5-methylphenyl group. This is followed by the condensation of the intermediate with 4-methylbenzophenone in the presence of a catalyst. The resulting product is then purified through recrystallization to obtain the desired compound. The process requires careful control of reaction conditions to ensure the desired purity and yield.

Applications of Octocrylene

Octocrylene is a key ingredient in sunscreens and skincare products due to its ability to protect the skin from UV radiation. It is often used in combination with other UV filters to provide broad-spectrum protection. In addition to sunscreens, Octocrylene is also found in makeup products, moisturizers, and lip balms. Its versatility makes it a popular choice in the cosmetic industry.

Safety Concerns and Regulatory Status

Octocrylene has been extensively evaluated for safety and has been deemed safe for use in cosmetics by regulatory agencies such as the U.S. Food and Drug Administration (FDA) and the European Union's Cosmetics Directive. However, concerns have been raised regarding its potential to cause allergic reactions and its photo-toxicity. Despite these concerns, Octocrylene remains a widely used UV filter due to its effectiveness and safety profile when used within recommended concentrations.

Environmental Impact of Octocrylene

Octocrylene has been found in the environment, particularly in coastal areas, where it is released through the use of sunscreen products. Its persistence in the environment has raised concerns about its potential ecological impact. Studies have shown that Octocrylene can be absorbed by marine organisms and may affect their health. Efforts are being made to develop alternative UV filters that are less harmful to the environment.

Conclusion

Octocrylene, with the chemical formula C24H27NO2 and CID 22571, is a widely used UV filter in the cosmetic industry. Its effectiveness in protecting the skin from harmful UV radiation makes it a valuable ingredient in sunscreens and skincare products. While concerns regarding its safety and environmental impact exist, regulatory agencies have deemed it safe for use when applied within recommended concentrations. As research continues to evolve, the role of Octocrylene in personal care products is likely to be further refined to ensure both safety and environmental responsibility.

Keywords

Octocrylene, C24H27NO2, CID 22571, UV filter, sunscreen, cosmetic industry, safety, environmental impact, regulatory status