This article delves into the chemical intricacies of CAS 120-35-4, also known as 3-Amino-4-methoxybenzanilide. It provides a comprehensive overview of its structure, synthesis, properties, and applications. By exploring its chemistry from various angles, including its molecular structure, synthesis methods, physical and chemical properties, biological activities, and uses in industry, this article aims to offer a comprehensive understanding of this compound.
3-Amino-4-methoxybenzanilide, with the CAS number 120-35-4, is a compound belonging to the class of aromatic amines. It is widely used in the synthesis of pharmaceuticals, agrochemicals, and dyes. This compound is characterized by its unique structure, which includes an amino group, a methoxy group, and a benzyl group. Its chemistry is of great interest due to its potential applications and the complexity of its synthesis.
The molecular structure of 3-Amino-4-methoxybenzanilide is a benzene ring with a methoxy group attached to the fourth position and an amino group attached to the third position. This arrangement of functional groups gives the compound its characteristic properties. The presence of the amino group makes it a basic compound, while the methoxy group contributes to its solubility in organic solvents. The benzyl group adds to its aromaticity, making it a versatile building block in organic synthesis.
The synthesis of 3-Amino-4-methoxybenzanilide can be achieved through various methods, including the reaction of 4-methoxybenzyl alcohol with aniline in the presence of a catalyst. This method involves the nucleophilic substitution of the hydroxyl group with the amino group. Another approach is the reaction of 4-methoxybenzyl chloride with aniline under basic conditions. These synthetic routes highlight the versatility of the compound and its derivatives in organic synthesis.
3-Amino-4-methoxybenzanilide is a white crystalline solid with a melting point of approximately 123-124°C. It is sparingly soluble in water but readily soluble in organic solvents such as ethanol, acetone, and chloroform. The compound is stable under normal conditions but may undergo degradation under acidic or alkaline conditions. These properties make it suitable for various applications in the chemical industry.
The biological activities of 3-Amino-4-methoxybenzanilide have been extensively studied. It has been found to exhibit antioxidant, anti-inflammatory, and antimicrobial properties. These activities are attributed to the presence of the amino and methoxy groups, which can interact with various biological molecules. The compound has potential applications in the development of new drugs for the treatment of various diseases.
3-Amino-4-methoxybenzanilide finds applications in various industries, including pharmaceuticals, agrochemicals, and dyes. In the pharmaceutical industry, it is used as a starting material for the synthesis of active pharmaceutical ingredients. In agrochemicals, it is used as a herbicide and insecticide. Additionally, it is used in the production of dyes and pigments due to its vibrant color and stability.
In conclusion, 3-Amino-4-methoxybenzanilide, with the CAS number 120-35-4, is a versatile compound with a wide range of applications. Its unique structure, synthesis methods, physical and chemical properties, biological activities, and industrial uses make it a subject of significant interest in the field of chemistry. This article has provided a comprehensive overview of the chemistry behind this compound, highlighting its importance and potential in various industries.
Keywords: 3-Amino-4-methoxybenzanilide, CAS 120-35-4, aromatic amines, synthesis, physical and chemical properties, biological activities, industrial applications.
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