This article provides an in-depth overview of CAS 14657-64-8, which refers to 3-hydroxyphenylphosphinyl-propanoic acid. The article delves into the chemical properties, synthesis methods, applications, safety considerations, and regulatory aspects of this compound. It aims to offer a comprehensive understanding of this chemical, its uses, and the importance of its proper handling and regulation.
CAS 14657-64-8, also known as 3-hydroxyphenylphosphinyl-propanoic acid, is a chemical compound with a unique structure and a range of potential applications. This compound is characterized by the presence of a hydroxyl group, a phosphine group, and a carboxylic acid group, which contribute to its chemical reactivity and versatility. Understanding the properties and uses of this compound is crucial for researchers, manufacturers, and regulatory bodies.
3-Hydroxyphenylphosphinyl-propanoic acid is a white to off-white solid that is soluble in organic solvents such as ethanol and acetone. It has a molecular formula of C9H10O4P and a molecular weight of 214.18 g/mol. The compound is slightly acidic due to the presence of the carboxylic acid group, which can react with bases to form salts. Its chemical reactivity is influenced by the presence of the phosphine group, which can undergo various substitution reactions.
The synthesis of 3-hydroxyphenylphosphinyl-propanoic acid involves several steps, including the preparation of the starting materials and the reaction conditions required for the formation of the desired compound. One common synthesis method involves the reaction of 3-hydroxyphenylacetone with phosphorus trichloride in the presence of a base. This reaction yields the phosphine oxide intermediate, which is then treated with propionic anhydride to form the final product. The process requires careful control of reaction conditions to ensure the desired yield and purity of the compound.
3-Hydroxyphenylphosphinyl-propanoic acid finds applications in various fields, including pharmaceuticals, agrochemicals, and organic synthesis. In the pharmaceutical industry, it can be used as a precursor for the synthesis of bioactive compounds. In agrochemicals, it may serve as an intermediate in the production of herbicides and pesticides. Additionally, its reactivity makes it a valuable reagent in organic synthesis, where it can be used to introduce phosphorus-containing groups into organic molecules.
Handling 3-hydroxyphenylphosphinyl-propanoic acid requires appropriate safety measures due to its potential hazards. The compound is irritant to the skin, eyes, and respiratory system. It is also toxic if ingested or inhaled. Therefore, it is essential to wear protective equipment, such as gloves, goggles, and a lab coat, when working with this chemical. Proper ventilation and adherence to safety protocols are crucial to prevent accidents and ensure the well-being of personnel.
The regulation of 3-hydroxyphenylphosphinyl-propanoic acid is governed by various international and national agencies. These regulations aim to ensure the safe handling, storage, and transportation of the compound. Compliance with these regulations is mandatory for manufacturers, distributors, and users of the chemical. The regulations may include labeling requirements, safety data sheets, and guidelines for waste disposal.
In conclusion, CAS 14657-64-8, or 3-hydroxyphenylphosphinyl-propanoic acid, is a versatile chemical compound with a range of potential applications. Its unique chemical properties, synthesis methods, and safety considerations make it an important compound in various industries. Understanding the regulatory aspects and proper handling of this compound is crucial for its safe and effective use. As research and development continue, the importance of this compound is likely to grow, necessitating a comprehensive understanding of its properties and applications.
Keywords: CAS 14657-64-8, 3-hydroxyphenylphosphinyl-propanoic acid, chemical properties, synthesis, applications, safety, regulation
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