This article provides an in-depth exploration of Formamide CAS 75-12-7, a crucial compound for researchers and scientists. It delves into the various applications, properties, safety considerations, and the importance of having a comprehensive resource dedicated to this chemical. The article aims to serve as a guide for those working with formamide, offering insights into its uses in research and industry.
Formamide, with the chemical abstracts service (CAS) number 75-12-7, is a simple organic compound that has found wide application in scientific research and industrial processes. It is a colorless, volatile liquid with a low boiling point, making it highly useful in various chemical reactions and biological studies. This article serves as a comprehensive resource for researchers and scientists, covering the essential aspects of formamide to aid in their work.
Formamide is a primary amide, characterized by the presence of a carbonyl group bonded to a nitrogen atom. Its molecular formula is CH2(O)NH, and it has a molecular weight of 45.05 g/mol. The compound is highly soluble in water, which is a key property for its use in biological systems. Formamide's low toxicity and stability make it a preferred solvent in many laboratory settings.
One of the notable properties of formamide is its ability to act as a polar aprotic solvent. This means it can dissolve a wide range of polar and ionic compounds without undergoing hydrolysis, which is particularly useful in chemical reactions where water would interfere. The polar nature of formamide also allows it to stabilize certain chemical species, making it a valuable tool in organic synthesis.
Formamide's versatility in scientific research is exemplified by its use in various fields. In molecular biology, formamide is employed as a denaturing agent in gel electrophoresis, which is crucial for separating DNA and RNA fragments based on size. Its ability to denature proteins and nucleic acids without causing significant degradation makes it ideal for such applications.
In the field of organic chemistry, formamide is used as a solvent for the synthesis of various organic compounds. Its polar aprotic nature facilitates the formation of amides and esters, which are essential intermediates in many chemical reactions. Additionally, formamide is used in the purification of organic compounds, as it can selectively dissolve certain substances while leaving others behind.
Formamide's biological significance is highlighted by its use in the study of proteins and nucleic acids. It is often used in the preparation of protein samples for gel electrophoresis, as it helps to maintain the native structure of proteins during the process. In the study of nucleic acids, formamide is used to denature DNA and RNA, allowing for the analysis of their sequences and structures.
Moreover, formamide has been found to have physiological effects in living organisms. It has been used in studies to investigate the effects of osmotic stress on cells, as it can mimic the osmotic environment found in certain biological systems. This makes formamide a valuable tool in understanding cellular responses to environmental changes.
While formamide is widely used in research and industry, it is important to consider its safety profile. The compound is toxic if ingested or inhaled, and it can cause irritation to the skin and eyes. Proper handling and storage procedures are essential to minimize the risk of exposure. Researchers and scientists should always wear appropriate personal protective equipment when working with formamide.
It is also important to note that formamide can react with strong oxidizing agents, producing harmful gases. Therefore, it should be stored away from such substances and in a cool, well-ventilated area. The use of formamide in enclosed spaces should be avoided, and proper ventilation should be ensured to prevent the accumulation of vapors.
The availability of a comprehensive resource like Formamide CAS 75-12-7: The Ultimate Resource for Researchers and Scientists is invaluable for anyone working with this compound. Such a resource provides detailed information on the chemical properties, applications, safety considerations, and regulatory information related to formamide. This ensures that researchers and scientists can make informed decisions and use the compound safely and effectively in their work.
Formamide CAS 75-12-7 is a versatile compound with significant applications in scientific research and industrial processes. Its unique chemical properties, combined with its biological significance, make it an essential tool for researchers and scientists. By providing a comprehensive overview of formamide, this resource aims to enhance the understanding and safe use of this compound in various fields.
Keywords: Formamide, CAS 75-12-7, chemical properties, scientific research, biological significance, safety considerations, comprehensive resource.
English (United States) 
English (Australia) 
Spanish 
Portuguese