This article provides an in-depth guide to 3-Methoxyphenol (CAS 150-19-6), a versatile organic compound with a wide range of uses and applications. It explores its chemical properties, synthesis methods, and detailed applications in various industries such as pharmaceuticals, agriculture, and materials science. The guide also discusses the safety and regulatory aspects associated with the compound, offering a comprehensive overview for professionals and researchers in the field.
3-Methoxyphenol, also known as 3-methylphenol, is an aromatic compound characterized by a benzene ring with a methoxy group attached to the third position. It is a colorless to pale yellow liquid with a characteristic odor. This compound is widely used in various industries due to its unique properties and versatility. In this guide, we will delve into the uses and applications of 3-Methoxyphenol, providing a comprehensive understanding of its role in different sectors.
3-Methoxyphenol possesses several chemical properties that make it suitable for various applications. It is a weak acid, with a pKa value of around 10.5, which allows it to act as a buffering agent in certain chemical reactions. The methoxy group attached to the benzene ring enhances the compound's solubility in organic solvents, making it easier to handle and process. Additionally, the aromatic nature of 3-Methoxyphenol makes it susceptible to electrophilic aromatic substitution reactions, which are crucial in its synthesis and transformation processes.
The synthesis of 3-Methoxyphenol can be achieved through various methods, including the reaction of phenol with methanol in the presence of a catalyst. This process is known as the Fries rearrangement and is one of the most common methods for producing 3-Methoxyphenol. Another synthesis route involves the reaction of chloromethylphenol with sodium hydroxide, followed by hydrolysis to yield the desired compound. These methods provide flexibility in the production of 3-Methoxyphenol, catering to the varying demands of different industries.
3-Methoxyphenol finds significant applications in the pharmaceutical industry. It serves as a precursor for the synthesis of various pharmaceutical intermediates and active pharmaceutical ingredients (APIs). For instance, it is used in the production of analgesics, antipyretics, and cardiovascular drugs. The compound's ability to undergo substitution reactions makes it a valuable building block in drug design and development. Moreover, its antioxidant properties make it a potential candidate for the development of new therapeutic agents.
In agriculture, 3-Methoxyphenol is utilized as a herbicide and fungicide. Its ability to inhibit the growth of certain plants and fungi makes it an effective tool for crop protection. The compound can be formulated into various agricultural products, such as sprays and granules, to combat pests and diseases that affect crop yields. Additionally, its low toxicity to humans and animals makes it a preferred choice for sustainable agricultural practices.
The unique properties of 3-Methoxyphenol make it a valuable compound in materials science. It is used in the synthesis of polymeric materials, such as polyesters and polyurethanes, which find applications in various industries, including automotive, construction, and electronics. The compound's ability to undergo polymerization reactions allows for the creation of materials with improved mechanical properties and durability. Furthermore, its flame-retardant properties make it a suitable additive for flame-retardant coatings and plastics.
The safe handling and use of 3-Methoxyphenol are crucial due to its potential health and environmental risks. It is classified as a hazardous substance, and appropriate safety measures must be taken during its storage, transportation, and use. The compound can cause irritation to the skin, eyes, and respiratory system, and exposure to high concentrations may lead to more severe health effects. Regulatory agencies, such as the Environmental Protection Agency (EPA) and the Occupational Safety and Health Administration (OSHA), have established guidelines and regulations to ensure the safe use of 3-Methoxyphenol.
In conclusion, 3-Methoxyphenol (CAS 150-19-6) is a versatile organic compound with a wide range of uses and applications. Its chemical properties, synthesis methods, and applications in various industries, such as pharmaceuticals, agriculture, and materials science, highlight its importance in modern society. Understanding the safety and regulatory aspects associated with the compound is essential for professionals and researchers working with 3-Methoxyphenol. This guide provides a comprehensive overview of the compound, offering valuable insights for those interested in its uses and applications.
Keywords: 3-Methoxyphenol, CAS 150-19-6, chemical properties, synthesis, pharmaceuticals, agriculture, materials science, safety, regulatory considerations.
English (United States) 
English (Australia) 
Spanish 
Portuguese