This article provides a comprehensive overview of 2,5-Dimethyl-3-hexyne-2,5-diol (CAS 142-30-3), a chemical compound with significant applications in various industries. The article delves into the chemical properties, synthesis methods, uses, safety considerations, and regulatory aspects of this compound, offering valuable insights for users and researchers in the field.
2,5-Dimethyl-3-hexyne-2,5-diol, also known as dimethylhex-2-en-1,5-diol, is a chemical compound with the molecular formula C8H14O2. It is a colorless liquid with a characteristic odor and is widely used in the synthesis of pharmaceuticals, flavors, and fragrances. This article aims to provide a detailed perspective on the must-know facts about this compound, focusing on its chemical properties, synthesis, applications, safety, and regulatory compliance.
2,5-Dimethyl-3-hexyne-2,5-diol is a diol compound, which means it contains two hydroxyl (-OH) groups. The presence of these hydroxyl groups makes it polar and soluble in water. The compound has a molecular weight of 138.21 g/mol and a melting point of -48.5°C. It is also characterized by its boiling point of 233°C and a density of 0.935 g/cm³ at 25°C. These properties make it a versatile compound for various applications.
The synthesis of 2,5-Dimethyl-3-hexyne-2,5-diol can be achieved through several methods, including the hydroxylation of dimethyl acetylene and the condensation of dimethyl acetylene with formaldehyde. The hydroxylation method involves the reaction of dimethyl acetylene with a hydroxylating agent, such as hydrogen peroxide or sodium hydroxide, in the presence of a catalyst. The condensation method involves the reaction of dimethyl acetylene with formaldehyde in the presence of a base, such as sodium hydroxide or potassium hydroxide. Both methods yield the desired compound with high purity.
2,5-Dimethyl-3-hexyne-2,5-diol finds extensive applications in the pharmaceutical industry, where it is used as a building block for the synthesis of various drugs. It is also used in the production of flavors and fragrances, particularly in the creation of fruity and floral notes. Additionally, the compound is employed in the synthesis of polymers, resins, and other chemical intermediates.
Handling 2,5-Dimethyl-3-hexyne-2,5-diol requires appropriate safety measures due to its potential hazards. The compound is flammable and can release toxic fumes when heated. It is also irritant to the skin, eyes, and respiratory system. Users should wear appropriate personal protective equipment, such as gloves, goggles, and a respirator, when handling this compound. Proper ventilation and adherence to safety protocols are crucial to prevent accidents and ensure a safe working environment.
2,5-Dimethyl-3-hexyne-2,5-diol is subject to regulatory compliance, particularly in the United States, where it is regulated under the Toxic Substances Control Act (TSCA). The compound must be registered with the Environmental Protection Agency (EPA) and comply with the applicable regulations. Users and manufacturers are responsible for ensuring that their operations are in compliance with these regulations to avoid legal and financial repercussions.
In conclusion, 2,5-Dimethyl-3-hexyne-2,5-diol (CAS 142-30-3) is a versatile chemical compound with significant applications in the pharmaceutical, flavor, and fragrance industries. Understanding its chemical properties, synthesis methods, uses, safety considerations, and regulatory compliance is essential for users and researchers in the field. By adhering to the guidelines outlined in this article, users can ensure safe and compliant handling of this compound, contributing to the advancement of scientific research and industrial applications.
Keywords: 2,5-Dimethyl-3-hexyne-2,5-diol, CAS 142-30-3, chemical properties, synthesis, applications, safety, regulatory compliance
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