**Exploring the Properties of 2-Phenoxyethanol CAS#122-99-6**
**Abstract:**
This article delves into the comprehensive properties of 2-phenoxyethanol (CAS#122-99-6), a versatile organic compound widely used in various industries. With a focus on its chemical structure, physical characteristics, applications, safety considerations, environmental impact, and regulatory status, this paper aims to provide a detailed overview of the compound's attributes and its significance in different fields. By examining these aspects, readers will gain a deeper understanding of 2-phenoxyethanol's role and potential implications.
2-Phenoxyethanol, with the chemical formula C8H10O2, is an organic compound that belongs to the family of glycol ethers. Its structure consists of a phenol group attached to an ethoxy chain. This unique structure gives 2-phenoxyethanol its distinct properties, making it a valuable compound in various applications.
The presence of the phenol group provides 2-phenoxyethanol with its characteristic aromatic scent, which is often described as sweet and floral. This property makes it a popular choice in the fragrance industry. Additionally, the ethoxy chain contributes to its solubility in both water and organic solvents, enhancing its versatility in different formulations.
The chemical stability of 2-phenoxyethanol is another crucial aspect of its structure. It is resistant to hydrolysis under normal conditions, which ensures its longevity in products where it is used as a preservative or stabilizer.
2-Phenoxyethanol is a colorless to pale yellow liquid with a slightly viscous consistency. Its physical properties make it suitable for a wide range of applications. One of the most notable characteristics is its boiling point, which is approximately 245°C. This high boiling point allows it to be used in products that require heat stability.
The compound has a relatively low vapor pressure, which means it does not easily evaporate at room temperature. This property is beneficial in applications where volatility is a concern, such as in paints and coatings. Furthermore, 2-phenoxyethanol has a relatively high flash point, making it less flammable and safer to handle in industrial settings.
Another important physical property is its solubility. 2-Phenoxyethanol is miscible with water and most organic solvents, including alcohols, ethers, and esters. This solubility profile makes it an excellent solvent and carrier in various formulations, including those used in the pharmaceutical and cosmetic industries.
The versatility of 2-phenoxyethanol has led to its widespread use in various industries. One of the primary applications is in the cosmetic industry, where it serves as a preservative, solvent, and fragrance component. Its ability to inhibit the growth of bacteria, yeast, and mold makes it an essential ingredient in skincare products, shampoos, and lotions.
In the pharmaceutical industry, 2-phenoxyethanol is used as a solvent for active pharmaceutical ingredients (APIs) and as a preservative in injectable solutions. Its compatibility with a wide range of drugs and its stability make it a preferred choice for many formulations.
Additionally, 2-phenoxyethanol finds applications in the printing industry as a solvent for ink and as a stabilizer in printing inks. Its ability to dissolve various pigments and resins makes it an important component in the production of high-quality prints.
While 2-phenoxyethanol is widely used, it is essential to consider its safety profile. The compound can be irritating to the skin and eyes, and prolonged exposure may lead to allergic reactions. Therefore, proper handling and safety measures are crucial when working with 2-phenoxyethanol.
Inhalation of the vapor can cause respiratory irritation, and ingestion can lead to gastrointestinal discomfort. To mitigate these risks, it is recommended to use personal protective equipment (PPE) such as gloves, goggles, and respiratory protection when handling the compound.
Regulatory agencies have established guidelines for the safe use of 2-phenoxyethanol. For example, the Cosmetic Ingredient Review (CIR) has determined that it is safe for use in cosmetic products when used at concentrations up to 1%.
The environmental impact of 2-phenoxyethanol is a significant consideration, especially in industries where it is widely used. The compound is biodegradable, which means it can be broken down by microorganisms in the environment. However, its biodegradation rate is relatively slow, which may lead to accumulation in aquatic systems if not properly managed.
2-Phenoxyethanol can be toxic to aquatic life, particularly to fish and algae, at certain concentrations. Therefore, industries using the compound must ensure proper waste treatment and disposal to minimize its impact on the environment.
Efforts are being made to develop more sustainable alternatives and improve waste management practices to reduce the environmental footprint of 2-phenoxyethanol.
The regulatory status of 2-phenoxyethanol varies by country and application. In the United States, the Food and Drug Administration (FDA) has classified it as a Generally Recognized as Safe (GRAS) substance for use in food and drugs. The Environmental Protection Agency (EPA) has also established regulations for its use in pesticides.
In the European Union, 2-phenoxyethanol is listed as a cosmetic ingredient and is subject to the EU Cosmetic Regulation. It is also regulated under the Registration, Evaluation, Authorisation, and Restriction of Chemicals (REACH) regulation.
The regulatory status of 2-phenoxyethanol is continuously monitored and updated based on new scientific evidence and emerging concerns, ensuring that its use remains safe and environmentally responsible.
In conclusion, 2-phenoxyethanol (CAS#122-99-6) is a versatile and valuable organic compound with a wide range of applications in various industries. Its unique chemical structure, physical characteristics, and safety profile make it an essential ingredient in cosmetics, pharmaceuticals, and other products. However, its environmental impact and regulatory status must be carefully considered to ensure its safe and sustainable use. By understanding the properties and implications of 2-phenoxyethanol, industries can continue to harness its benefits while minimizing potential risks.
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