**1-Octanol CAS#111-87-5: A Comprehensive Guide**

**Abstract:**
This comprehensive guide provides an in-depth analysis of 1-Octanol, a chemical compound with the CAS number 111-87-5. The article delves into its physical and chemical properties, uses, production methods, health and safety considerations, environmental impact, and regulatory aspects. By examining these various dimensions, the guide aims to offer a thorough understanding of 1-Octanol and its significance in various industries.

1. Introduction to 1-Octanol CAS#111-87-5

1-Octanol, also known as octan-1-ol, is a colorless liquid with a characteristic sweet odor. It belongs to the alcohol family and is widely used in the chemical industry. With the CAS number 111-87-5, 1-Octanol is known for its versatility and is utilized in a range of applications, from cosmetics to industrial processes.

2. Physical and Chemical Properties

Physical Properties

1-Octanol is a colorless liquid at room temperature with a molecular formula of C8H18O. It has a boiling point of approximately 195°C and a melting point of -17°C. The compound is slightly soluble in water but miscible with most organic solvents. Its density is around 0.824 g/cm³, making it lighter than water.

Chemical Properties

Chemically, 1-Octanol is an alcohol, which means it contains a hydroxyl group (-OH) attached to an octane chain. This functional group makes it reactive and capable of forming various chemical bonds. It can undergo dehydration reactions to form alkenes and can also be oxidized to form octanoic acid.

Odor and Taste

1-Octanol has a sweet, floral odor that is often described as pleasant. However, it has a pungent taste, which is why it is not commonly used in food applications.

3. Uses of 1-Octanol

Industrial Applications

1-Octanol is widely used in the manufacturing of various industrial chemicals. It serves as a precursor for the production of esters, which are used in the production of plastics, resins, and synthetic rubber. Additionally, it is used in the synthesis of detergents, surfactants, and corrosion inhibitors.

Cosmetics and Personal Care

In the cosmetics industry, 1-Octanol is used as a solvent and fragrance ingredient. It is found in perfumes, lotions, and other personal care products due to its pleasant odor. The compound also acts as a fixative, helping to prolong the scent of fragrances.

Pharmaceuticals

1-Octanol finds application in the pharmaceutical industry as a solvent for various drugs. It is used in the formulation of oral and topical medications, contributing to their stability and effectiveness.

4. Production Methods

Hydroformylation Process

The primary industrial method for producing 1-Octanol is through the hydroformylation of octene. This process involves the reaction of octene with carbon monoxide and hydrogen in the presence of a catalyst, typically cobalt or rhodium. The resulting aldehyde is then hydrogenated to form 1-Octanol.

Alcoholysis of Esters

Another method involves the alcoholysis of esters derived from octanoic acid. This process uses an alcohol, such as ethanol or methanol, to convert the ester into 1-Octanol and the corresponding carboxylic acid.

Biotechnological Production

Recent advancements in biotechnology have enabled the production of 1-Octanol through microbial fermentation. This sustainable method utilizes genetically modified microorganisms to convert renewable resources into 1-Octanol, offering an alternative to traditional chemical processes.

5. Health and Safety Considerations

Exposure Risks

Exposure to 1-Octanol can occur through inhalation, skin contact, or ingestion. High levels of exposure can lead to respiratory irritation, skin irritation, and central nervous system depression. It is important to handle the compound with care to minimize these risks.

Personal Protective Equipment (PPE)

To mitigate the risks associated with 1-Octanol, appropriate personal protective equipment should be used. This includes gloves, safety goggles, and respiratory protection when handling the compound in high concentrations or in confined spaces.

Regulatory Aspects

The use of 1-Octanol is regulated by various agencies, including the Environmental Protection Agency (EPA) and the Occupational Safety and Health Administration (OSHA). These regulations ensure that the compound is used safely and that its disposal does not harm the environment.

6. Environmental Impact

Biodegradability

1-Octanol is considered biodegradable, which means it can be broken down by microorganisms in the environment. This property reduces its potential for long-term environmental impact.

Toxicity

While 1-Octanol is biodegradable, it can be toxic to aquatic life if released into water bodies in high concentrations. It is important to manage the disposal of 1-Octanol properly to prevent environmental contamination.

Green Chemistry

Efforts are being made to develop greener production methods for 1-Octanol, such as biotechnological processes that reduce the reliance on fossil fuels and minimize waste. These approaches align with the principles of green chemistry and contribute to sustainable development.

Conclusion

In conclusion, 1-Octanol CAS#111-87-5 is a versatile and important chemical compound with a wide range of applications in various industries. Its physical and chemical properties make it suitable for use in cosmetics, pharmaceuticals, and industrial processes. Understanding its production methods, health and safety considerations, and environmental impact is crucial for ensuring its safe and sustainable use. By adhering to regulatory guidelines and embracing green chemistry principles, the industry can continue to harness the benefits of 1-Octanol while minimizing its potential drawbacks.