Chemical Analysis of 1-Octanol CAS#111-87-5

August 8, 2024

Chemical Analysis of 1-Octanol CAS#111-87-5

Abstract

This article provides a comprehensive analysis of 1-Octanol (CAS#111-87-5), a chemical compound widely used in various industries. The analysis covers its physical and chemical properties, analytical methods, applications, safety considerations, environmental impact, and regulatory aspects. Through this detailed examination, the article aims to offer a thorough understanding of the compound's characteristics and its significance in different fields.

1. Physical and Chemical Properties

1-Octanol, also known as octan-1-ol, is a colorless liquid with a characteristic alcohol odor. It has a molecular formula of C8H18O and a molecular weight of 130.23 g/mol. The compound is soluble in water and miscible with most organic solvents. Its boiling point is approximately 195°C, and its melting point is around -17°C. 1-Octanol is a primary alcohol, which means it has a hydroxyl group (-OH) attached to the end carbon of the octane chain.

Chemically, 1-Octanol is relatively stable under normal conditions. It can undergo various reactions, such as esterification, etherification, and oxidation. The presence of the hydroxyl group makes it a versatile compound for chemical synthesis. Its physical and chemical properties make it suitable for a wide range of applications in industries such as pharmaceuticals, cosmetics, and flavoring agents.

2. Analytical Methods

Several analytical methods are employed to identify and quantify 1-Octanol in various matrices. Gas chromatography (GC) is one of the most commonly used techniques for the analysis of volatile organic compounds, including 1-Octanol. GC coupled with mass spectrometry (MS) provides additional confirmation of the compound's identity and structure.

Liquid chromatography (LC) is another technique used for the analysis of 1-Octanol, especially in complex matrices. High-performance liquid chromatography (HPLC) with a refractive index detector or a UV detector can be employed to separate and quantify the compound. Additionally, Fourier transform infrared (FTIR) spectroscopy can be used to identify functional groups present in 1-Octanol, providing structural information.

These analytical methods are crucial for ensuring the purity and quality of 1-Octanol in industrial applications. They also help in detecting any impurities or contaminants that may affect the compound's performance or safety.

3. Applications

1-Octanol finds extensive use in various industries due to its unique properties. In the pharmaceutical industry, it serves as a solvent for drugs and as a starting material for the synthesis of active pharmaceutical ingredients (APIs). Its solubility in both water and organic solvents makes it an ideal choice for formulation development.

In the cosmetic industry, 1-Octanol is used as a fragrance ingredient and as a solvent for other cosmetic ingredients. It contributes to the sensory experience of products and helps in the dispersion of other components. Additionally, 1-Octanol is employed in the production of flavoring agents, providing a characteristic taste to food and beverages.

Other applications include its use as a solvent in paints, coatings, and adhesives. It is also utilized in the synthesis of esters, ethers, and other derivatives, which have various industrial applications.

4. Safety Considerations

While 1-Octanol is widely used in various industries, it is essential to consider its safety aspects. The compound is flammable and can cause irritation to the skin and eyes upon contact. Inhalation of its vapors may lead to respiratory distress and central nervous system depression.

Proper handling and storage are crucial to minimize the risks associated with 1-Octanol. It should be stored in a cool, dry place, away from heat and ignition sources. Personal protective equipment (PPE), such as gloves, goggles, and respiratory protection, should be used when handling the compound.

In case of accidental exposure, immediate first aid measures should be taken, including washing the affected area with water and seeking medical attention if necessary. It is also important to follow the guidelines and regulations set by regulatory bodies to ensure the safe use of 1-Octanol.

5. Environmental Impact

The environmental impact of 1-Octanol is an important consideration in its industrial use. The compound is biodegradable, but its high solubility in water can lead to aquatic toxicity if released into the environment. It is essential to prevent spills and leaks during transportation and storage to minimize its impact on aquatic ecosystems.

Proper waste disposal methods should be employed to ensure that 1-Octanol does not contaminate soil and water sources. Recycling and recovery processes can also be implemented to reduce the environmental footprint of the compound. Additionally, the use of alternative, more environmentally friendly solvents can be explored to minimize the reliance on 1-Octanol.

Regulatory agencies and industries are increasingly focusing on the environmental impact of chemicals, and 1-Octanol is no exception. Compliance with environmental regulations and guidelines is crucial to ensure the sustainable use of the compound.

6. Regulatory Aspects

1-Octanol is subject to various regulations and guidelines in different countries and regions. The compound is listed in the European Union's (EU) Registration, Evaluation, Authorisation, and Restriction of Chemicals (REACH) regulation, which aims to protect human health and the environment from the risks associated with chemicals.

In the United States, 1-Octanol is regulated by the Environmental Protection Agency (EPA) under the Toxic Substances Control Act (TSCA). It is also classified as a hazardous substance under the Occupational Safety and Health Administration (OSHA) Hazard Communication Standard.

Compliance with these regulations is essential for industries using 1-Octanol. Companies must ensure proper labeling, safety data sheets, and handling procedures to meet the requirements set by regulatory bodies. Adherence to these regulations helps in minimizing the risks associated with the compound and promoting its safe and responsible use.

Conclusion

In conclusion, 1-Octanol (CAS#111-87-5) is a versatile chemical compound with a wide range of applications in various industries. Its physical and chemical properties make it suitable for use as a solvent, fragrance ingredient, and starting material for synthesis. However, its safety, environmental impact, and regulatory aspects must be carefully considered to ensure its responsible use.

Through the detailed analysis presented in this article, we have explored the various dimensions of 1-Octanol, from its physical and chemical properties to its applications, safety considerations, environmental impact, and regulatory aspects. By understanding these aspects, industries can make informed decisions regarding the use of 1-Octanol, ensuring both its effectiveness and safety.

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