{"id":10321,"date":"2024-11-13T15:17:14","date_gmt":"2024-11-13T07:17:14","guid":{"rendered":"https:\/\/chemneo.com\/product\/10321.html"},"modified":"2024-11-13T15:17:14","modified_gmt":"2024-11-13T07:17:14","slug":"2-tetrahydrofuroic-acid-cas-16874-33-2-2","status":"publish","type":"product","link":"https:\/\/chemneo.com\/en\/product\/10321.html","title":{"rendered":"2-Tetrahydrofuroic Acid CAS 16874-33-2"},"content":{"rendered":"<p>Description<\/p>\n<p>\t2-Tetrahydrofuroic acid Details<br \/>\nChemical Name: 2-Tetrahydrofuroic acid<br \/>\nSynonyms: Tetrahydrofurioic Acid; Tetrahydro-2-furoic Acid; T2F; THFC; THFAC; 2-THFA\uff0ctetrahydrofuran-2-carboxylic acid; 2-tetrahydrofuoic acid; 2-tetrahydrofuoic acid<br \/>\nCAS No.: 16874-33-2<br \/>\nMolecular Formula: C5H8O3<br \/>\nMolecular Weight: 116.12<br \/>\nMolecular\u00a0Structure:<\/p>\n<p>Appearance:\u00a0Colorless\u00a0to\u00a0light\u00a0yellow\u00a0liquidAssay: 99%<br \/>\nTypical\u00a0Properties<\/p>\n<p>Melting point<br \/>\n21\u00b0C<\/p>\n<p>Boiling point<br \/>\n128-129\u00a0\u00b0C13\u00a0mm Hg(lit.)<\/p>\n<p>Density<br \/>\n1.209\u00a0g\/mL\u00a0at 25\u00a0\u00b0C(lit.)<\/p>\n<p>Water Solubility<br \/>\nsoluble<\/p>\n<p>Appearance<br \/>\nLiquid<\/p>\n<p>Colour<br \/>\nTransparent yellow to brown<\/p>\n<p>Refractive index<br \/>\nn20\/D 1.46 (lit.)<\/p>\n<p>2-Tetrahydrofuroic acid Usage<br \/>\n2-Tetrahydrofuran-2-carboxylicacid (2-THFA) can be split into (R)-2-THFA and (S)-2-THFA. Chiral 2-tetrahydrofurancarboxylicacid is an important ligand synthon in asymmetric synthesis reactions. Among them, (R)-2-THFA is an important intermediate for the synthesis of the antibiotic furopenem, which can be used as an antagonist of the antigen VLA-4, and is also a chiral resolution agent for an important intermediate of the super flu drug Xofluza; (S)-2-THFA is the main raw material for the preparation of the chiral auxiliary (S)-acetyltetrahydrofuran, a raw material for the preparation of cephalosporin antibiotic intermediates, and an important intermediate for the preparation of the hormone LHRH that stimulates hormone release.<br \/>\nPackaging and Shipping<br \/>\n200kg\/drum<br \/>\n2-Tetrahydrofuroic acid Storage<br \/>\nIt\u00a0should\u00a0be\u00a0stored\u00a0in\u00a0a\u00a0clean,\u00a0dry\u00a0and\u00a0cool\u00a0place,\u00a0preventing\u00a0from\u00a0sunlight,\u00a0rain.<\/p>","protected":false},"excerpt":{"rendered":"<p>Chemical Name: 2-Tetrahydrofuroic acid<br \/>\nSynonyms: Tetrahydro-2-furoic Acid; T2F; THFC; THFAC<br \/>\nCAS No.: 16874-33-2<br \/>\nMolecular Formula: C5H8O3<br \/>\nMolecular Weight: 116.12<br \/>\nAppearance: Liquid<\/p>","protected":false},"featured_media":6542,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[17],"product_tag":[],"class_list":{"0":"post-10321","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-uncategorized","8":"first","9":"instock","10":"shipping-taxable","11":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/chemneo.com\/en\/wp-json\/wp\/v2\/product\/10321","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/chemneo.com\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/chemneo.com\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/chemneo.com\/en\/wp-json\/wp\/v2\/comments?post=10321"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/chemneo.com\/en\/wp-json\/wp\/v2\/media\/6542"}],"wp:attachment":[{"href":"https:\/\/chemneo.com\/en\/wp-json\/wp\/v2\/media?parent=10321"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/chemneo.com\/en\/wp-json\/wp\/v2\/product_brand?post=10321"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/chemneo.com\/en\/wp-json\/wp\/v2\/product_cat?post=10321"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/chemneo.com\/en\/wp-json\/wp\/v2\/product_tag?post=10321"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}