{"id":132,"date":"2024-08-06T01:56:31","date_gmt":"2024-08-06T01:56:31","guid":{"rendered":"https:\/\/chemneo.com\/?post_type=product&#038;p=132"},"modified":"2024-08-06T01:57:06","modified_gmt":"2024-08-06T01:57:06","slug":"arbutin-cas497-76-7","status":"publish","type":"product","link":"https:\/\/chemneo.com\/en\/product\/132.html","title":{"rendered":"Arbutin CAS#497-76-7"},"content":{"rendered":"<div id=\"ContentPlaceHolder1_ProductChemPropertyA\">\n<table border=\"0\" width=\"100%\" cellspacing=\"1\" cellpadding=\"2\" bgcolor=\"d5d5d5\">\n<tbody>\n<tr class=\"ProdSupplierGN_ProductA_1\">\n<td class=\"td12\">Melting point<\/td>\n<td bgcolor=\"#fafafa\"><span style=\"color: #0066cc;\">195-198\u00a0\u00b0C<\/span><\/td>\n<\/tr>\n<tr class=\"ProdSupplierGN_ProductA_2\">\n<td bgcolor=\"#FFFFFF\">Boiling point<\/td>\n<td bgcolor=\"#FFFFFF\"><span style=\"color: #0066cc;\">375.31\u00b0C (rough estimate)<\/span><\/td>\n<\/tr>\n<tr class=\"ProdSupplierGN_ProductA_1\">\n<td class=\"td12\">alpha<\/td>\n<td bgcolor=\"#fafafa\"><span style=\"color: #0066cc;\">-64 \u00ba (c=3)<\/span><\/td>\n<\/tr>\n<tr class=\"ProdSupplierGN_ProductA_2\">\n<td bgcolor=\"#FFFFFF\">density<\/td>\n<td bgcolor=\"#FFFFFF\"><span style=\"color: #0066cc;\">1.3582 (rough estimate)<\/span><\/td>\n<\/tr>\n<tr class=\"ProdSupplierGN_ProductA_1\">\n<td class=\"td12\">refractive index<\/td>\n<td bgcolor=\"#fafafa\"><span style=\"color: #0066cc;\">-65.5 \u00b0 (C=4, H2O)<\/span><\/td>\n<\/tr>\n<tr class=\"ProdSupplierGN_ProductA_2\">\n<td bgcolor=\"#FFFFFF\">storage temp.<\/td>\n<td bgcolor=\"#FFFFFF\"><span style=\"color: #0066cc;\">Inert atmosphere,Room Temperature<\/span><\/td>\n<\/tr>\n<tr class=\"ProdSupplierGN_ProductA_1\">\n<td class=\"td12\">solubility<\/td>\n<td bgcolor=\"#fafafa\"><span style=\"color: #0066cc;\">H<sub>2<\/sub>O: 50\u00a0mg\/mL hot, clear<\/span><\/td>\n<\/tr>\n<tr class=\"ProdSupplierGN_ProductA_2\">\n<td bgcolor=\"#FFFFFF\">form<\/td>\n<td bgcolor=\"#FFFFFF\"><span style=\"color: #0066cc;\">Solid<\/span><\/td>\n<\/tr>\n<tr class=\"ProdSupplierGN_ProductA_1\">\n<td class=\"td12\">pka<\/td>\n<td bgcolor=\"#fafafa\"><span style=\"color: #0066cc;\">10.10\u00b10.15(Predicted)<\/span><\/td>\n<\/tr>\n<tr class=\"ProdSupplierGN_ProductA_2\">\n<td bgcolor=\"#FFFFFF\">color<\/td>\n<td bgcolor=\"#FFFFFF\"><span style=\"color: #0066cc;\">White<\/span><\/td>\n<\/tr>\n<tr class=\"ProdSupplierGN_ProductA_1\">\n<td class=\"td12\">optical activity<\/td>\n<td bgcolor=\"#fafafa\"><span style=\"color: #0066cc;\">[\u03b1]\/D -64.0\u00b12.0\u00b0, c = 3 in H2O<\/span><\/td>\n<\/tr>\n<tr class=\"ProdSupplierGN_ProductA_2\">\n<td bgcolor=\"#FFFFFF\">Water Solubility<\/td>\n<td bgcolor=\"#FFFFFF\"><span style=\"color: #0066cc;\">10-15 g\/100 mL at 20 \u00baC<\/span><\/td>\n<\/tr>\n<tr class=\"ProdSupplierGN_ProductA_1\">\n<td class=\"td12\">Sensitive<\/td>\n<td bgcolor=\"#fafafa\"><span style=\"color: #0066cc;\">Hygroscopic<\/span><\/td>\n<\/tr>\n<tr class=\"ProdSupplierGN_ProductA_2\">\n<td bgcolor=\"#FFFFFF\">Merck<\/td>\n<td bgcolor=\"#FFFFFF\"><span style=\"color: #0066cc;\">14,773<\/span><\/td>\n<\/tr>\n<tr class=\"ProdSupplierGN_ProductA_1\">\n<td class=\"td12\">BRN<\/td>\n<td bgcolor=\"#fafafa\"><span style=\"color: #0066cc;\">89673<\/span><\/td>\n<\/tr>\n<tr class=\"ProdSupplierGN_ProductA_2\">\n<td bgcolor=\"#FFFFFF\">Stability:<\/td>\n<td bgcolor=\"#FFFFFF\"><span style=\"color: #0066cc;\">Stable. Hygroscopic - store under dry nitrogen.<\/span><\/td>\n<\/tr>\n<tr class=\"ProdSupplierGN_ProductA_1\">\n<td class=\"td12\">InChIKey<\/td>\n<td bgcolor=\"#fafafa\"><span style=\"color: #0066cc;\">BJRNKVDFDLYUGJ-RMPHRYRLSA-N<\/span><\/td>\n<\/tr>\n<tr class=\"ProdSupplierGN_ProductA_2\">\n<td bgcolor=\"#FFFFFF\">LogP<\/td>\n<td bgcolor=\"#FFFFFF\"><span style=\"color: #0066cc;\">-1.350<\/span><\/td>\n<\/tr>\n<tr class=\"ProdSupplierGN_ProductA_1\">\n<td class=\"td12\">CAS DataBase Reference<\/td>\n<td bgcolor=\"#fafafa\"><span style=\"color: #0066cc;\"><a title=\"497-76-7(CAS DataBase Reference)\" href=\"https:\/\/www.chemicalbook.com\/CAS_497-76-7.htm\" target=\"_blank\" rel=\"noopener\">497-76-7(CAS DataBase Reference)<\/a><\/span><\/td>\n<\/tr>\n<tr class=\"ProdSupplierGN_ProductA_2\">\n<td bgcolor=\"#FFFFFF\">EPA Substance Registry System<\/td>\n<td bgcolor=\"#FFFFFF\"><span style=\"color: #0066cc;\"><a title=\".beta.-D-Glucopyranoside, 4-hydroxyphenyl (497-76-7)\" href=\"https:\/\/ofmpub.epa.gov\/sor_internet\/registry\/substreg\/searchandretrieve\/substancesearch\/search.do?details=displayDetails&amp;selectedSubstanceId=98524\" rel=\"nofollow noopener\" target=\"_blank\">.beta.-D-Glucopyranoside, 4-hydroxyphenyl (497-76-7)<\/a><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<div id=\"ContentPlaceHolder1_ProductChemSafePropertyA\">\n<table border=\"0\" width=\"100%\" cellspacing=\"0\" cellpadding=\"0\" align=\"center\">\n<tbody>\n<tr>\n<td bgcolor=\"64B7D7\" height=\"1\"><\/td>\n<\/tr>\n<tr>\n<td class=\"td6\" bgcolor=\"DEEEF4\" width=\"611\" height=\"23\">Safety Information<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table border=\"0\" width=\"100%\" cellspacing=\"1\" cellpadding=\"2\" bgcolor=\"d5d5d5\">\n<tbody>\n<tr class=\"ProdSupplierGN_ProductA_1\">\n<td class=\"td12\">Hazard Codes<\/td>\n<td bgcolor=\"#fafafa\"><span style=\"color: #0066cc;\"><a href=\"https:\/\/www.chemicalbook.com\/RiskAndSafety.htm#hazards\" target=\"_blank\" rel=\"noopener\">Xn<\/a><\/span><\/td>\n<\/tr>\n<tr class=\"ProdSupplierGN_ProductA_2\">\n<td bgcolor=\"#FFFFFF\">Risk Statements<\/td>\n<td bgcolor=\"#FFFFFF\"><span style=\"color: #0066cc;\"><a href=\"https:\/\/www.chemicalbook.com\/RiskAndSafety.htm#Risk\" target=\"_blank\" rel=\"noopener\">20\/21\/22-36\/37\/38<\/a><\/span><\/td>\n<\/tr>\n<tr class=\"ProdSupplierGN_ProductA_1\">\n<td class=\"td12\">Safety Statements<\/td>\n<td bgcolor=\"#fafafa\"><span style=\"color: #0066cc;\"><a href=\"https:\/\/www.chemicalbook.com\/RiskAndSafety.htm#Safety\" target=\"_blank\" rel=\"noopener\">22-24\/25-36-26<\/a><\/span><\/td>\n<\/tr>\n<tr class=\"ProdSupplierGN_ProductA_2\">\n<td bgcolor=\"#FFFFFF\">WGK Germany<\/td>\n<td bgcolor=\"#FFFFFF\"><span style=\"color: #0066cc;\">3<\/span><\/td>\n<\/tr>\n<tr class=\"ProdSupplierGN_ProductA_1\">\n<td class=\"td12\">RTECS<\/td>\n<td bgcolor=\"#fafafa\"><span style=\"color: #0066cc;\">CE8863000<\/span><\/td>\n<\/tr>\n<tr class=\"ProdSupplierGN_ProductA_2\">\n<td bgcolor=\"#FFFFFF\">F<\/td>\n<td bgcolor=\"#FFFFFF\"><span style=\"color: #0066cc;\"><a href=\"https:\/\/www.chemicalbook.com\/RiskAndSafety.htm#hazards\" target=\"_blank\" rel=\"noopener\">3-10-23<\/a><\/span><\/td>\n<\/tr>\n<tr class=\"ProdSupplierGN_ProductA_1\">\n<td class=\"td12\">HS Code<\/td>\n<td bgcolor=\"#fafafa\"><span style=\"color: #0066cc;\">29389090<\/span><\/td>\n<\/tr>\n<tr class=\"ProdSupplierGN_ProductA_2\">\n<td bgcolor=\"#FFFFFF\">Hazardous Substances Data<\/td>\n<td bgcolor=\"#FFFFFF\"><span style=\"color: #0066cc;\"><a title=\"497-76-7(Hazardous Substances Data)\" href=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/source\/hsdb\/7661\" rel=\"nofollow noopener\" target=\"_blank\">497-76-7(Hazardous Substances Data)<\/a><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Arbutin, a derivative of hydroquinone, is a naturally occurring compound extracted primarily from the bearberry plant (Arctostaphylos uva-ursi). It is renowned in the skincare industry for its skin lightening properties, making it a popular ingredient in cosmetic products designed to reduce hyperpigmentation and even out skin tone.<\/p>\n<p>Chemically, arbutin is \u03b2-glucosiduronic acid of hydroquinone, with the molecular formula C12H12O7. Its mechanism of action involves the inhibition of tyrosinase, a key enzyme in the melanin biosynthesis pathway. By reducing melanin production, arbutin effectively lightens the skin without the risk of irritation often associated with hydroquinone.<\/p>\n<p>Arbutin is valued for its safety profile, as it is considered less irritating and more stable compared to other skin lightening agents. It is also known for its antioxidant properties, which contribute to its skin brightening effects and overall skin health benefits.<\/p>\n<p class=\"last-node\">In summary, arbutin is a reliable and gentle alternative for skin lightening, offering a natural approach to reducing pigmentation issues while promoting a more radiant and even complexion. Its use in skincare formulations is favored for its efficacy and mildness, making it suitable for various skin types.<\/p>","protected":false},"featured_media":200,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[22],"product_tag":[24],"class_list":{"0":"post-132","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-daily-chemicals","7":"product_tag-daily-chemicals","9":"first","10":"instock","11":"shipping-taxable","12":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/chemneo.com\/en\/wp-json\/wp\/v2\/product\/132","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/chemneo.com\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/chemneo.com\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/chemneo.com\/en\/wp-json\/wp\/v2\/comments?post=132"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/chemneo.com\/en\/wp-json\/wp\/v2\/media\/200"}],"wp:attachment":[{"href":"https:\/\/chemneo.com\/en\/wp-json\/wp\/v2\/media?parent=132"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/chemneo.com\/en\/wp-json\/wp\/v2\/product_brand?post=132"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/chemneo.com\/en\/wp-json\/wp\/v2\/product_cat?post=132"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/chemneo.com\/en\/wp-json\/wp\/v2\/product_tag?post=132"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}