{"id":4129,"date":"2024-08-28T03:05:32","date_gmt":"2024-08-28T03:05:32","guid":{"rendered":"https:\/\/chemneo.com\/?post_type=product&p=4129"},"modified":"2024-08-28T03:06:34","modified_gmt":"2024-08-28T03:06:34","slug":"urapidil-hydrochloride-cas-34661-75-1","status":"publish","type":"product","link":"https:\/\/chemneo.com\/en\/product\/4129.html","title":{"rendered":"Urapidil Hydrochloride CAS# 34661-75-1"},"content":{"rendered":"

Urapidil Hydrochloride CAS# 34661-75-1<\/p>\n

\n\n\n\n
6-[[3-[4-(2-Methoxyphenyl)-1-piperazinyl]propyl]amino]-1,3-dimethyluracil Basic information<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n\n\n\n\n\n\n\n\n
Product Name:<\/td>\n6-[[3-[4-(2-Methoxyphenyl)-1-piperazinyl]propyl]amino]-1,3-dimethyluracil<\/td>\n<\/tr>\n
Synonyms:<\/td>\n1,3-dimethyl-6-(3-(4-(o-methoxyphenyl)-1-piperazinyl)proppylamino)-uraci<\/span>;6-(3-(4-(o-methoxyphenyl)-1-piperazinyl)propylamino)-1,3-dimethyluracil<\/span>;b-66256<\/span>;6-[[3-[4-(2-methoxyphenyl)-1-piperazinyl]propyl]amino]-1,3-dimethyluracil<\/span>;UrapidilC20H29N503<\/span>;URAPIDIL [6-((3-(4-(2-METHOXYPHENYL)-1-PIPERAZINYL)PROPYL)AMINO)-1,3-DIMETHYLURACIL]<\/span>;1,3-Dimethyl-6-[3-[4-(o-methoxyphenyl)piperazin-1-yl]propylamino]uracil<\/span>;BKU<\/span><\/td>\n<\/tr>\n
CAS:<\/td>\n34661-75-1<\/b><\/td>\n<\/tr>\n
MF:<\/td>\nC20H29N5O3<\/td>\n<\/tr>\n
MW:<\/td>\n387.48<\/td>\n<\/tr>\n
EINECS:<\/td>\n252-130-4<\/td>\n<\/tr>\n
Product Categories:<\/td>\nEBRANTIL;API;API's;34661-75-1<\/td>\n<\/tr>\n
Mol File:<\/td>\n34661-75-1.mol<\/td>\n<\/tr>\n
\"6-[[3-[4-(2-Methoxyphenyl)-1-piperazinyl]propyl]amino]-1,3-dimethyluracil<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n
\n\n\n\n\n
<\/td>\n<\/tr>\n
6-[[3-[4-(2-Methoxyphenyl)-1-piperazinyl]propyl]amino]-1,3-dimethyluracil Chemical Properties<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Melting point<\/td>\n156-158\u00b0<\/span><\/td>\n<\/tr>\n
Boiling point<\/td>\n513.42\u00b0C (rough estimate)<\/span><\/td>\n<\/tr>\n
density<\/td>\n1.2058 (rough estimate)<\/span><\/td>\n<\/tr>\n
refractive index<\/td>\n1.7600 (estimate)<\/span><\/td>\n<\/tr>\n
storage temp.<\/td>\nSealed in dry,Room Temperature<\/span><\/td>\n<\/tr>\n
solubility<\/td>\nDMSO: 25 mg\/mL (64.52 mM); Water: < 0.1 mg\/mL (insoluble)<\/span><\/td>\n<\/tr>\n
form<\/td>\npowder to crystal<\/span><\/td>\n<\/tr>\n
pka<\/td>\n7.10(at 25\u2103)<\/span><\/td>\n<\/tr>\n
color<\/td>\nWhite to Light yellow to Light orange<\/span><\/td>\n<\/tr>\n
\u03bbmax<\/td>\n268nm(MeOH)(lit.)<\/span><\/td>\n<\/tr>\n
Merck<\/td>\n14,9865<\/span><\/td>\n<\/tr>\n
CAS DataBase Reference<\/td>\n34661-75-1(CAS DataBase Reference)<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n
\n\n\n\n\n
<\/td>\n<\/tr>\n
Safety Information<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n\n\n\n\n\n
Hazard Codes<\/td>\nXn<\/span><\/td>\n<\/tr>\n
Risk Statements<\/td>\n22-36\/37\/38<\/span><\/td>\n<\/tr>\n
Safety Statements<\/td>\n26<\/span><\/td>\n<\/tr>\n
RTECS<\/td>\nYQ9862000<\/span><\/td>\n<\/tr>\n
HS Code<\/td>\n2933.59.8000<\/span><\/td>\n<\/tr>\n
Toxicity<\/td>\nLD50 in male mice, rats (mg\/kg): 750, 550 orally; 260, 145 i.v. (Koenig)<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>","protected":false},"excerpt":{"rendered":"

Urapidil is a sympathetic antihypertensive drug. It acts as \u03b1 1 \u2013 adrenoceptor antagonists and 5-HT 1A receptor agonists act. Although the initial report showed that urapidil was also a \u03b1 2 \u2013 adrenoceptor agonist, which was not confirmed in later studies, proved that it had no agonist effect in the saphenous vein of dogs and ileum of guinea pigs. With others \u03b1 Unlike 1-adrenoceptor villains, urapidil does not cause response tachycardia, which may be connected to its weak \u03b2 1-adrenoceptor antagonist activity and its impact on heart vagal drive. Urapidil has actually not been approved by the US Food and drug administration, yet it is offered in Europe.<\/p>\n

Urapidil (URA), chemical name is 6-[[3-[4-(2-methoxyphenyl)-1-piperazinyl]propyl]amino]-1,3-dimethyl -2,4(1H,3H)-pyrimidinedione, trade name: ebrantil (ebrantil), synonym: excellent matchi, uracil substituted by phenazine.<\/strong><\/p>","protected":false},"featured_media":4190,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[22],"product_tag":[24],"class_list":{"0":"post-4129","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-daily-chemicals","7":"product_tag-daily-chemicals","9":"first","10":"instock","11":"shipping-taxable","12":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/chemneo.com\/en\/wp-json\/wp\/v2\/product\/4129","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/chemneo.com\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/chemneo.com\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/chemneo.com\/en\/wp-json\/wp\/v2\/comments?post=4129"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/chemneo.com\/en\/wp-json\/wp\/v2\/media\/4190"}],"wp:attachment":[{"href":"https:\/\/chemneo.com\/en\/wp-json\/wp\/v2\/media?parent=4129"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/chemneo.com\/en\/wp-json\/wp\/v2\/product_brand?post=4129"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/chemneo.com\/en\/wp-json\/wp\/v2\/product_cat?post=4129"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/chemneo.com\/en\/wp-json\/wp\/v2\/product_tag?post=4129"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}