This article serves as the ultimate resource for 4-Nitro-3-Trifluoromethyl Aniline CAS 393-11-3, providing a comprehensive overview of its properties, synthesis, applications, safety, and regulatory information. It aims to serve as a guide for researchers, chemists, and professionals in the field, ensuring they have access to all the necessary information to understand and utilize this compound effectively.
4-Nitro-3-Trifluoromethyl Aniline, with the CAS number 393-11-3, is a chemical compound that has gained significant attention in various scientific and industrial applications. This compound is characterized by the presence of a nitro group and a trifluoromethyl group attached to an aniline backbone. Its unique structure and properties make it a valuable compound in research and development.
4-Nitro-3-Trifluoromethyl Aniline is a solid compound that is typically obtained as a white to off-white crystalline powder. It has a melting point of approximately 102-104°C and a boiling point of around 312°C. The compound is soluble in organic solvents such as acetone, chloroform, and benzene, but it is sparingly soluble in water. Its molecular formula is C6H5NNO2F3, and it has a molecular weight of 197.13 g/mol.
The synthesis of 4-Nitro-3-Trifluoromethyl Aniline involves several steps, including the nitration of aniline and the subsequent trifluoromethylation. The nitration process typically involves the use of nitric acid and sulfuric acid as reagents, while the trifluoromethylation is achieved through the reaction with triflic anhydride. The overall reaction scheme is complex and requires careful control of reaction conditions to ensure the desired product is obtained.
4-Nitro-3-Trifluoromethyl Aniline finds applications in various fields, including pharmaceuticals, agrochemicals, and organic synthesis. In the pharmaceutical industry, it is used as an intermediate in the synthesis of active pharmaceutical ingredients (APIs). It is also employed in the production of agrochemicals, such as herbicides and insecticides, due to its ability to enhance the bioactivity of these compounds. Additionally, its unique properties make it a valuable compound in organic synthesis, where it can be used as a building block for the construction of more complex molecules.
Handling 4-Nitro-3-Trifluoromethyl Aniline requires caution due to its potential hazards. The compound is considered toxic and can cause irritation to the skin, eyes, and respiratory system. It is essential to wear appropriate personal protective equipment (PPE) when working with this compound, including gloves, goggles, and a lab coat. Adequate ventilation is also crucial to prevent the accumulation of vapors in the workplace. In case of accidental exposure, immediate medical attention should be sought.
The production, import, and export of 4-Nitro-3-Trifluoromethyl Aniline are subject to various regulations and guidelines. These regulations are in place to ensure the safe handling and use of the compound and to protect human health and the environment. Compliance with these regulations is essential for businesses involved in the production, distribution, and use of this compound.
In conclusion, 4-Nitro-3-Trifluoromethyl Aniline CAS 393-11-3 is a versatile compound with significant applications in various industries. This article has provided a comprehensive overview of its chemical properties, synthesis, applications, safety, and regulatory information. Understanding these aspects is crucial for researchers, chemists, and professionals working with this compound, ensuring its effective and safe utilization.
Keywords: 4-Nitro-3-Trifluoromethyl Aniline, CAS 393-11-3, chemical properties, synthesis, applications, safety, regulatory information
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