{"id":3873,"date":"2024-08-28T03:00:39","date_gmt":"2024-08-28T03:00:39","guid":{"rendered":"https:\/\/chemneo.com\/?post_type=product&p=3873"},"modified":"2024-08-28T03:01:36","modified_gmt":"2024-08-28T03:01:36","slug":"idebenone-cas-58186-27-9","status":"publish","type":"product","link":"https:\/\/chemneo.com\/pt\/product\/3873.html","title":{"rendered":"Idebenona CAS 58186-27-9"},"content":{"rendered":"

Idebenona CAS 58186-27-9<\/p>\n

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Idebenone Basic information<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n\n\n\n\n\n\n\n\n
Product Name:<\/td>\nIdebenone<\/td>\n<\/tr>\n
Synonyms:<\/td>\ncv 2619 idebenone;Daruma\uff1aMnesis;2,5-Cyclohexadiene-1,4-dione, 5,6-dimethoxy-2-(10-hydroxydecyl)-3-methyl-;6-(10-Hydroxydecyl)ubiquinone;2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-dione;2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-p-benzoquinone;IDEBENONE(P);2-(10-Hydroxydecyl)-5\uff0c6-dimethoxy-3-methyl-2\uff0c5-cyclohexadienPl\uff0c4-dione<\/td>\n<\/tr>\n
CAS:<\/td>\n58186-27-9<\/b><\/td>\n<\/tr>\n
MF:<\/td>\nC19H30O5<\/td>\n<\/tr>\n
MW:<\/td>\n338.44<\/td>\n<\/tr>\n
EINECS:<\/td>\n1308068-626-2<\/td>\n<\/tr>\n
Product Categories:<\/td>\nAromatics;API;Other APIs;AP;Anthraquinones, Hydroquinones and Quinones;Cnbio;Intermediates & Fine Chemicals;Pharmaceuticals;58186-27-9<\/td>\n<\/tr>\n
Mol File:<\/td>\n58186-27-9.mol<\/td>\n<\/tr>\n
\"Idebenone<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n
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<\/td>\n<\/tr>\n
Idebenone Chemical Properties<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Melting point<\/td>\n52-550C<\/span><\/td>\n<\/tr>\n
Ponto de ebuli\u00e7\u00e3o<\/td>\n497.3\u00b145.0 \u00b0C(Predicted)<\/span><\/td>\n<\/tr>\n
densidade<\/td>\n1.08\u00b10.1 g\/cm3(Predicted)<\/span><\/td>\n<\/tr>\n
storage temp.<\/td>\nroom temp<\/span><\/td>\n<\/tr>\n
solubility<\/td>\nSoluble in DMSO (up to 25 mg\/ml).<\/span><\/td>\n<\/tr>\n
forma<\/td>\nSolid<\/span><\/td>\n<\/tr>\n
pka<\/td>\n15.20\u00b10.10(Predicted)<\/span><\/td>\n<\/tr>\n
color<\/td>\nOrange<\/span><\/td>\n<\/tr>\n
Merck<\/td>\n14,4888<\/span><\/td>\n<\/tr>\n
Estabilidade:<\/td>\nStable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20\u00b0C for up to 3 months.<\/span><\/td>\n<\/tr>\n
InChI<\/td>\nInChI=1S\/C19H30O5\/c1-14-15(12-10-8-6-4-5-7-9-11-13-20)17(22)19(24-3)18(23-2)16(14)21\/h20H,4-13H2,1-3H3<\/span><\/td>\n<\/tr>\n
InChIKey<\/td>\nJGPMMRGNQUBGND-UHFFFAOYSA-N<\/span><\/td>\n<\/tr>\n
SMILES<\/td>\nC1(=O)C(OC)=C(OC)C(=O)C(C)=C1CCCCCCCCCCO<\/span><\/td>\n<\/tr>\n
LogP<\/td>\n3.490 (est)<\/span><\/td>\n<\/tr>\n
CAS DataBase Reference<\/td>\n58186-27-9(CAS DataBase Reference)<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n
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<\/td>\n<\/tr>\n
Informa\u00e7\u00f5es de seguran\u00e7a<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n\n\n\n
Hazard Codes<\/td>\nXi<\/span><\/td>\n<\/tr>\n
WGK Germany<\/td>\n3<\/span><\/td>\n<\/tr>\n
RTECS<\/td>\nGU5290000<\/span><\/td>\n<\/tr>\n
HS Code<\/td>\n2933399990<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>","protected":false},"excerpt":{"rendered":"

A idebenona \u00e9 um composto org\u00e2nico com o nome qu\u00edmico: 6-(10-hidroxidecil)-2,3-dimetoxi-5-metil-1,4-benzoquinona. \u00c9 um an\u00e1logo estrutural da coenzima Q10 e est\u00e1 a ser desenvolvido pela Takeda Pharmaceuticals como um medicamento para o tratamento de doen\u00e7as cognitivas como a doen\u00e7a de Alzheimer.<\/p>\n

A idebenona tem um efeito ativador na fun\u00e7\u00e3o mitocondrial, melhora o metabolismo cerebral e a disfun\u00e7\u00e3o cerebral, e pode aumentar a taxa de utiliza\u00e7\u00e3o da glicose no c\u00e9rebro e promover a gera\u00e7\u00e3o de ATP; melhora o metabolismo do neurotransmissor 5-hidroxitriptamina no c\u00e9rebro e tem um forte efeito antioxidante e de elimina\u00e7\u00e3o de radicais livres. Na pr\u00e1tica cl\u00ednica, \u00e9 utilizado principalmente para tratar muitas doen\u00e7as degenerativas do sistema nervoso central relacionadas com o stress oxidativo, como a doen\u00e7a de Parkinson, a doen\u00e7a de Alzheimer, a dem\u00eancia multi-infarto, a anemia cerebral local e a insufici\u00eancia cerebral, etc. \u00c9 tamb\u00e9m utilizada para tratar a ataxia de Friedreich. Tamb\u00e9m pode ser utilizado em f\u00f3rmulas cosm\u00e9ticas, com efic\u00e1cia cosm\u00e9tica, como a elimina\u00e7\u00e3o de radicais livres, a inibi\u00e7\u00e3o da peroxida\u00e7\u00e3o lip\u00eddica, a inibi\u00e7\u00e3o da inflama\u00e7\u00e3o, a inibi\u00e7\u00e3o dos danos no ADN, a prote\u00e7\u00e3o contra a luz e a redu\u00e7\u00e3o da pigmenta\u00e7\u00e3o.<\/p>","protected":false},"featured_media":3916,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[22],"product_tag":[24],"class_list":{"0":"post-3873","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-daily-chemicals","7":"product_tag-daily-chemicals","9":"first","10":"instock","11":"featured","12":"shipping-taxable","13":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/chemneo.com\/pt\/wp-json\/wp\/v2\/product\/3873","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/chemneo.com\/pt\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/chemneo.com\/pt\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/chemneo.com\/pt\/wp-json\/wp\/v2\/comments?post=3873"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/chemneo.com\/pt\/wp-json\/wp\/v2\/media\/3916"}],"wp:attachment":[{"href":"https:\/\/chemneo.com\/pt\/wp-json\/wp\/v2\/media?parent=3873"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/chemneo.com\/pt\/wp-json\/wp\/v2\/product_brand?post=3873"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/chemneo.com\/pt\/wp-json\/wp\/v2\/product_cat?post=3873"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/chemneo.com\/pt\/wp-json\/wp\/v2\/product_tag?post=3873"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}