{"id":4026,"date":"2024-08-28T03:03:25","date_gmt":"2024-08-28T03:03:25","guid":{"rendered":"https:\/\/chemneo.com\/?post_type=product&p=4026"},"modified":"2024-08-28T03:04:43","modified_gmt":"2024-08-28T03:04:43","slug":"copper-tripeptide-1-cas-130120-57-9","status":"publish","type":"product","link":"https:\/\/chemneo.com\/pt\/product\/4026.html","title":{"rendered":"Tripept\u00eddeo de cobre-1 CAS 130120-57-9"},"content":{"rendered":"
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Tripept\u00eddeo de cobre-1 CAS 130120-57-9<\/p>\n\n\n\n
Prezatide copper acetate Basic information<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n\n\n\n\n\n\n\n\n
Product Name:<\/td>\nPrezatide copper acetate<\/td>\n<\/tr>\n
Synonyms:<\/td>\nPrezatide copper acetate;GHK-Cu, >=98%;Copper peptide, Copper Tripeptide-3, AHK Copper;Anti-allergic & Skin Repair Series AHK - Cu \/GHK-Cu\/ Copper Peptide;Copper Tripeptide-3 (AHK-Cu);Tripeptide-1 copper (copper peptide);Pure copper peptide ghk-cu\/ghk cu copper tripeptide-1 prezatide copper acetate;copper,aceticacid,(2S)-6-amino-2-[[(2S)-2-[(2-aminoacetyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoicaci<\/td>\n<\/tr>\n
CAS:<\/td>\n130120-57-9<\/b><\/td>\n<\/tr>\n
MF:<\/td>\nC30H48CuN12O10<\/td>\n<\/tr>\n
MW:<\/td>\n800.33<\/td>\n<\/tr>\n
EINECS:<\/td>\n000-000-0<\/td>\n<\/tr>\n
Product Categories:<\/td>\nAPIs;130120-57-9<\/td>\n<\/tr>\n
Mol File:<\/td>\n130120-57-9.mol<\/td>\n<\/tr>\n
\"Prezatide<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n
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Prezatide copper acetate Chemical Properties<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n\n\n
InChIKey<\/td>\nVJKXESGORYEAGC-UHFFFAOYSA-K<\/span><\/td>\n<\/tr>\n
SMILES<\/td>\nC(=O)(O)C.C(C1CC2=CNC=N2[Cu+2]2(N3C=NC(CC(NC(=O)CN)C(=O)NC(C(=O)[O-])CCCCN)=C3)NCC(=O)[N-]12)(=O)NC(C(=O)[O-])CCCCN.[H+]<\/span><\/td>\n<\/tr>\n
LogP<\/td>\n-2.241 (est)<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n
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Informa\u00e7\u00f5es de seguran\u00e7a<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n
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Informa\u00e7\u00e3o MSDS<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
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Prezatide copper acetate Usage And Synthesis<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n\n\n\n\n\n\n
Descri\u00e7\u00e3o<\/td>\nIamin gel was launched in the US for the care of chronic and acute wounds. It can be prepared by combining the tripeptide GHK and copper (\u2161) acetate. There are several species present in equilibrium but the biscomplex is the dominant compound at neutral pH. The GHK sequence is found in only eight human proteins and is an endogenous growth factor that stimulates collagen synthesis and angiogenesis. This is part of the explanation for its wound healing and tissue repair ability. It can significantly delay fibroblast activation, is a growth factor for hepatocyctes, neurons, thyroid follicular cells and is a chemoattractant for monocytes, macrophages, mast cells and capillary endothelial cells. Copper is also known to have an effect on lysyl oxidase which is a key enzyme involved in collagen formation.<\/span><\/td>\n<\/tr>\n
Originator<\/td>\nProCyte (USA)<\/span><\/td>\n<\/tr>\n
Utiliza\u00e7\u00f5es<\/td>\nanti-wrikle<\/span><\/td>\n<\/tr>\n
Utiliza\u00e7\u00f5es<\/td>\nPrezatide is used for skin care, and has the potential to treat chronic obstructive pulmonary disease and metastatic colon cancer. Prezatide copper acetate is used in personal skin care products with anti-inflammatory and anti-allergic effects, such as essence lotion, cream, facial mask and sunscreen, etc<\/span><\/td>\n<\/tr>\n
Brand name<\/td>\nIamin (ProCyte).<\/span><\/td>\n<\/tr>\n
Mechanism of action<\/td>\nCopper peptides, including Prezatide, are known for their potent biological activity, primarily due to copper's essential role in various enzymatic processes. In wound healing, Prezatide copper acetate promotes angiogenesis (the formation of new blood vessels), which is critical for supplying nutrients and oxygen to the wound site. This process is facilitated by activating growth factors such as vascular endothelial growth factor (VEGF) and transforming growth factor-beta (TGF-\u03b2). Additionally, Prezatide copper acetate exhibits significant anti-inflammatory properties. It inhibits the production of pro-inflammatory cytokines, thereby reducing inflammation and promoting a conducive environment for tissue repair. The compound also boosts the synthesis of extracellular matrix components like collagen and elastin, which are vital for maintaining skin integrity and elasticity, thus explaining its use in dermatological applications.<\/span><\/td>\n<\/tr>\n
Side effects<\/td>\nCommonly reported side effects from topical application include skin irritation, redness, and itching at the site. These are generally mild and tend to resolve with continued use or after product discontinuation. More severe allergic reactions are rare but can occur, manifesting as swelling, severe itching, or difficulty breathing, which would require immediate medical attention.
\nSystemic administration of Prezatide copper acetate may present a different side effect profile. Patients could experience symptoms such as nausea, vomiting, headache, dizziness, and, in some cases, gastrointestinal disturbances. Due to the involvement of copper, there is also a potential risk of copper toxicity, particularly in patients with underlying conditions that affect copper metabolism, such as Wilson\u2019s disease. Therefore, it is crucial to monitor copper levels in the body during treatment.<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>","protected":false},"excerpt":{"rendered":"

P\u00e9ptido de acetato de cobre, tamb\u00e9m conhecido como p\u00e9ptido de cobre azul. Pept\u00eddeo de cobre, tamb\u00e9m conhecido como tripept\u00eddeo em chin\u00eas; Glycyl-L-histomyl-L-lysine. O p\u00e9ptido \u00e9 uma pequena mol\u00e9cula de prote\u00edna composta por amino\u00e1cidos, que s\u00e3o mais facilmente absorvidos pela pele e t\u00eam efeitos mais significativos. Foi isolado pela primeira vez do plasma humano em 1973 e descobriu-se que tinha uma fun\u00e7\u00e3o de repara\u00e7\u00e3o de feridas em 1985. Em 1999, os investigadores acreditavam que o p\u00e9ptido de cobre e os seus produtos de repara\u00e7\u00e3o de cobre podem servir como activadores da remodela\u00e7\u00e3o dos tecidos, e \u00e9 tamb\u00e9m um p\u00e9ptido de sinaliza\u00e7\u00e3o, promovendo a degrada\u00e7\u00e3o de uma grande quantidade de agregados de colag\u00e9nio fora das cicatrizes, a s\u00edntese de colag\u00e9nio normal na pele, a gera\u00e7\u00e3o de elastina, proteoglicanos e glicanos de glucosamina, a taxa de crescimento e migra\u00e7\u00e3o de diferentes tipos de c\u00e9lulas, respostas anti-inflamat\u00f3rias e antioxidantes.<\/p>","protected":false},"featured_media":4083,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[22],"product_tag":[24],"class_list":{"0":"post-4026","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-daily-chemicals","7":"product_tag-daily-chemicals","9":"first","10":"instock","11":"shipping-taxable","12":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/chemneo.com\/pt\/wp-json\/wp\/v2\/product\/4026","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/chemneo.com\/pt\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/chemneo.com\/pt\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/chemneo.com\/pt\/wp-json\/wp\/v2\/comments?post=4026"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/chemneo.com\/pt\/wp-json\/wp\/v2\/media\/4083"}],"wp:attachment":[{"href":"https:\/\/chemneo.com\/pt\/wp-json\/wp\/v2\/media?parent=4026"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/chemneo.com\/pt\/wp-json\/wp\/v2\/product_brand?post=4026"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/chemneo.com\/pt\/wp-json\/wp\/v2\/product_cat?post=4026"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/chemneo.com\/pt\/wp-json\/wp\/v2\/product_tag?post=4026"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}