{"id":4230,"date":"2024-08-28T03:07:09","date_gmt":"2024-08-28T03:07:09","guid":{"rendered":"https:\/\/chemneo.com\/?post_type=product&p=4230"},"modified":"2024-08-28T03:08:02","modified_gmt":"2024-08-28T03:08:02","slug":"coenzyme-a-sodium-salt-cas-55672-92-9","status":"publish","type":"product","link":"https:\/\/chemneo.com\/pt\/product\/4230.html","title":{"rendered":"SAL DE S\u00d3DIO DA COENZIMA A CAS# 55672-92-9"},"content":{"rendered":"

SAL DE S\u00d3DIO DA COENZIMA A CAS# 55672-92-9<\/p>\n

\n\n\n\n
COENZYME A SODIUM SALT Basic information<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n\n\n\n\n\n\n\n\n
Product Name:<\/td>\nCOENZYME A SODIUM SALT<\/td>\n<\/tr>\n
Synonyms:<\/td>\nCoenzymeA hydrate sodium salt<\/span>;coenzyme A sodium from yeast<\/span>;COENZYME A, SODIUM CELL CULTURE TESTED<\/span>;COENZYME A DISODIUM SALT<\/span>;COENZYME A SODIUM SALT<\/span>;COENZYME A SODIUM SALT HYDRATE<\/span>;COENZYME A TRISODIUM SALT<\/span>;COA NA2<\/span><\/td>\n<\/tr>\n
CAS:<\/td>\n55672-92-9<\/b><\/td>\n<\/tr>\n
MF:<\/td>\nC21H35N7NaO16P3S<\/td>\n<\/tr>\n
MW:<\/td>\n789.52<\/td>\n<\/tr>\n
EINECS:<\/td>\n259-747-8<\/td>\n<\/tr>\n
Product Categories:<\/td>\n<\/td>\n<\/tr>\n
Mol File:<\/td>\n55672-92-9.mol<\/td>\n<\/tr>\n
\"COENZYME<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n
\n\n\n\n\n
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COENZYME A SODIUM SALT Chemical Properties<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n\n
storage temp.<\/td>\n\u221220\u00b0C<\/span><\/td>\n<\/tr>\n
solubility<\/td>\nH2O: soluble50mg\/mL, clear, colorless to faintly yellow<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n
\n\n\n\n\n
<\/td>\n<\/tr>\n
Informa\u00e7\u00f5es de seguran\u00e7a<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n\n\n
Safety Statements<\/td>\n22-24\/25<\/span><\/td>\n<\/tr>\n
WGK Germany<\/td>\n3<\/span><\/td>\n<\/tr>\n
F<\/td>\n3-10-23<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n
\n\n\n\n\n
<\/td>\n<\/tr>\n
Informa\u00e7\u00e3o MSDS<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
\n\n\n\n\n
Provider<\/th>\nLanguage<\/th>\n<\/tr>\n
SigmaAldrich<\/td>\nEnglish<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div>\n
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COENZYME A SODIUM SALT Usage And Synthesis<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n\n\n
Utiliza\u00e7\u00f5es<\/td>\nCoenzyme A is suitable for use in:
\n<\/span><\/p>\n
    \n
  • gylcerolipid biosynthesis in porcine adipose tissue<\/li>\n
  • an assay to measure the level of Alpha-methylacyl-CoA racemase (AMACR) in human blood samples using a nanoparticle electrochemical biosensor<\/li>\n
  • chloramphenicol acetyltransferase (CAT) assay<\/li>\n
  • the synthesis of palmitoyl-CoA, which is required for palmitoylation and activation of proteins for regulated membrane fusion<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n
General Description<\/td>\nCoenzyme A (CoA) is an essential cofactor in living systems and is synthesized from pantothenic acid (vitamin B5), The CoA levels in mitochondria and peroxisomes correspond to 2-5 mM and 0.7 mM, respectively. Cytosolic CoA is in the range of 0.05 mM to 0.14 mM<\/span><\/td>\n<\/tr>\n
Biochem\/physiol Actions<\/td>\nCoenzyme A (CoA, CoASH, HSCoA) is a coenzyme that facilitates enzymatic acyl-group transfer reactions and supports the synthesis and oxidation of fatty acids. CoA is involved in the mechanisms of a wide variety of enzymes. In the presence of CoASH, organic carboxylic acids form acyl-CoA thioesters, which facilitates enzyme recognition. The acyl-CoA formed from xenobiotic carboxylic acids can add to the compound\u2032s toxicity, which can lead to cellular metabolic dysfunction. It is involved in the oxidation of pyruvate in the Kreb\u2032s cycle. CoA is needed for metabolic events. The bacterial CoA pathway is targeted for antimicrobial development. It mediates acyl group transfer and carbonyl activation. The CoA and its thioester levels are crucial for cellular homeostasis. CoA is also involved in regulating platelet aggregation and vasoconstriction. It acts as an essential cofactor in enzymatic acetyl transfer reactions.<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>","protected":false},"excerpt":{"rendered":"

O sal de s\u00f3dio hidratado da coenzima A (CAS 55672-92-9) \u00e9 uma importante subst\u00e2ncia biologicamente ativa.
\nAspeto: Normalmente p\u00f3 branco ou esbranqui\u00e7ado. Solubilidade: Facilmente sol\u00favel em \u00e1gua, formando uma solu\u00e7\u00e3o l\u00edmpida em \u00e1gua.
\nFun\u00e7\u00e3o: No organismo, o sal s\u00f3dico hidratado da coenzima A \u00e9 uma coenzima importante que participa numa variedade de reac\u00e7\u00f5es bioqu\u00edmicas. Desempenha um papel fundamental no metabolismo dos \u00e1cidos gordos, promovendo a ativa\u00e7\u00e3o e a decomposi\u00e7\u00e3o oxidativa dos \u00e1cidos gordos. Participa no ciclo do \u00e1cido tricarbox\u00edlico e fornece energia \u00e0s c\u00e9lulas. \u00c9 tamb\u00e9m importante para o metabolismo de certos amino\u00e1cidos.
\nAplica\u00e7\u00e3o: Utilizado habitualmente na investiga\u00e7\u00e3o em bioqu\u00edmica e biologia molecular como cofator para reac\u00e7\u00f5es enzim\u00e1ticas.
\nNo dom\u00ednio da medicina, pode ser utilizado no tratamento ou no tratamento adjuvante de certas doen\u00e7as.<\/p>","protected":false},"featured_media":4280,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[18],"product_tag":[19],"class_list":{"0":"post-4230","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-petroleum-additives","7":"product_tag-petroleum-additives","9":"first","10":"instock","11":"shipping-taxable","12":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/chemneo.com\/pt\/wp-json\/wp\/v2\/product\/4230","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/chemneo.com\/pt\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/chemneo.com\/pt\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/chemneo.com\/pt\/wp-json\/wp\/v2\/comments?post=4230"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/chemneo.com\/pt\/wp-json\/wp\/v2\/media\/4280"}],"wp:attachment":[{"href":"https:\/\/chemneo.com\/pt\/wp-json\/wp\/v2\/media?parent=4230"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/chemneo.com\/pt\/wp-json\/wp\/v2\/product_brand?post=4230"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/chemneo.com\/pt\/wp-json\/wp\/v2\/product_cat?post=4230"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/chemneo.com\/pt\/wp-json\/wp\/v2\/product_tag?post=4230"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}